Heart Diseases Result From Obesity Even When The Obese Does Not Suffer From Diabetes Or Have High Cholesterol
Date: 20th November 2008
According to a striking revelation, Ohio University researchers utilized superior nanosensor technology to highlight several mechanisms taking place in the human body that are responsible for connecting obesity with heart diseases. Sources also reveal that the results of the study revolve around the hormone leptin and lead to the conclusion that heart diseases can be ultimate outcome of obesity even when the individual suffering from obesity is not a victim of high cholesterol/diabetes.
Specific results obtained from the Ohio university experiment disclose that when the levels of leptin hormone are increased in the blood of an obese individual, certain reactions take place that further augment the risk of heart diseases. Nitric oxide is a chemical compound necessary for relaxing arteries and accelerate smooth blood flow and and the increasing leptin levels cause reduction in the level of nitric oxide. Altogether, the excessive amount of leptin levels present in blood increases the production of superoxide and when this super oxide forms reactions with nitric oxide, peroxynitrite is created. The peroxynitrite molecule causes destruction to the endothelial cells, and also interferes with the DNA levels.
The study initiated by the Ohio university researchers lead to the conclusion that regardless of whether an obese individual is a victim of high cholesterol, diabetes or any other cardiovascular risk factor, the leptin hormone unleashes certain effects on the cardiovascular system of the body that augments the risk of falling prey to heart diseases.
Source: http://www.wellnessresources.com/ |