Researchers Evaluate Gene Mutation As A Powerful Factor In Offering Protection Against Diabetes And Obesity
Date: 20th October 2008
According to a special identification by a group of researchers from the “German Institute of Human Nutrition”, a certain form of mutation in the gene Tbc1d1 is capable of offering adequate protection to mice against obesity as well as diabetes in spite of a high fat diet, therefore it is expected that the advantages of this gene mutation phenomena would be the same pertaining to diabetes and obesity in humans and thus can offer a foundation for developing new approaches towards prevention as well as treatment of diabetes and obesity.
Sources reveal that Hans-Georg Joost and Hadi Al-Hasan are the two prominent researchers who have played a leading role in the gene identification program. However, explaining the role played by gene mutation in fat, glucose and energy metabolism, Hadi Al-Hasani makes it apparent that the mutation process eliminates the Tbc1d1 gene which further results in fat consumption in the skeletal muscle and altogether increases fat oxidation. He therefore adds that, in this process, glucose consumption of the muscles is decreased and thus it becomes clear that the Tbc1d1 gene plays a significant role in glucose and fat metabolism and altogether regulates energy metabolism.
Hans-Georg Joost states how our body uses the food we eat and also, perform an important role in the development of diabetes and obesity. Further, it is also known that as soon as the relationship between glucose and fat oxidation is altered, the muscle utilizes less glucose and more fat as a fundamental resource of energy As a consequence, the body stores less fat and this makes the individual less prone to obesity as well as to diabetes, a direct consequence of obesity.
Source: http://www.sciencedaily.com/ |
